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CYTOXAN
Drug information
This medicine contains active ingredient called cyclophosphamide and is used for treatment of certain types of cancers like breast cancer, lymphoma, leukemia, multiple myeloma, mycosis fungoides, neuroblastoma, retinoblastoma, testicular cancer, lung cancer and ovarian cancer. It is generally given in combination with other medicines. It may also be used for certain kidney problems like nephritic syndrome in children.
Mechanism
Cytoxan is an anti-cancer or antineoplastic chemotherapy drug. Cyclophosphamide is an alkylation agent, which are most active in resting phase of cell. This drug induces beneficial immunomodulatory effects in adaptive immunotherapy. The mechanism includes elimination of T regulatory cells in tumor bearing hosts, induction of T cell growth factors, enhanced grafting of adoptively transferred, tumor reactive effectors T cells. The drug works effectively when it is taken exactly as prescribed by the doctor for the full treatment period prescribed for.
How to take Cytoxan
The dosage of Cytoxan depends on certain factors like the type of conditions a person is suffering from, severity of infection, height, weight, age and sex of the patient.
It is given orally with food or after meals. The tablets should not be crushed or chewed. Usual oral dose ranges from 1 to 5 mg/kg/day for initial and maintenance dose.
It may be prescribed for any other condition by your doctor. It is available in injection form of 500mg, 1.0mg, and 2.0mg strength and in tablet form in 25mg and 50 mg strength.
Injections are given through veins. Shot is given in muscles (IM), abdominal lining (IP) or into the lining of the lung (Intrapleural).
Drink plenty of water and urinate frequently, while taking this medicine, especially in first 24 hours of intake of medicine.
Do not skip any dose and take the medicine strictly as prescribed by your doctor.
There may be certain side effects of the medicine like low blood count which can temporarily make you anemic, temporary hair loss, nausea, poor appetite, loss of fertility, discoloration of skin and nails, diarrhea, mouth sore, unusual bleeding or any other. In case any symptom becomes severe immediately take medical help.
Precautions
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